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Cardiac & Anti-Diabetic

Home »  Products » Cardiac & Anti-Diabetic  » Glamor-PM tablets
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Glamor-PM Tablets

Glimepiride USP 2mg+Metformin Hydrochloride IP 500mg+Pioglitazone Hydrochloride 15mg

 

INDICATIONS

Type 2 Diabetes 

Hyperinsulinemia

For the management of Polycystic Ovarian Syndrome (PCOS)

As an adjunct to diet in patients with NIDDM.

 

Glimepiride

Medium -to -long active sulfonyurea antidiabetic drug that stimulates the of the body's natural insulin.

Stimulates the insulin release from functioning pancreatic beta cells & inhibits gluconeogensis at hepatic cells.

Acts as an insulin secretagogue by lowering blood sugar level with increased activity of intercelluar insulin receptors.

Increases insulin sensitivity at peripheral target sites.

 

Metformin

Decreases blood sugar levels by lowering hepatic glucose production & intestinal absorptiomn of glucose.

Improves insulin sensitivity by increasing peripheral glucose uptake and utilization.

Reduces glucose absorption from the GI tract and reduces gluconeogensis.

Helps reduces LDL cholesterol and triglyceride levels and is not associated with weight gain.

 

Pioglitazone

Acts as an agonist at peroxisome proliferators activated receptors in target tissue for insulin action such as adipose tissue,skeletal muscle and liver.

Activation of PPAR-gamma receptors increases the transcription of insulin-responsive genes involved in the control of glucose production transport & utilization.

Enhances tissue sensitivity to insulin and reduces hepatic gluconeogensis.

Shows efficacy in improving glycaemic control in patients with type 2 diabetes.

 

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