PREGANERVE-N TABLET
(Pregabalin 75mg+Nortriptyline 10mg)
INDICATIONS:
Neuropathic pain associated with diabetic peripherial neuropathy
Adjunctive theraphy for adult patients with partial onset seizures
Fibromyalgia
DOSAGE:
Twice daily or as directed by physician
EXPLAINATION:
Pregabalin:
It reduces the synaptic release of several neurotransmitters by binding to alpha2-delta subunits,and thus,reduces neuronal excitability and seizures.
Effective in reducing pain and improving sleep disturbances due to diabetic pain.
Nortriptyline:
Effectively manages neuropathic pain through inhibition of serotonin and norepinephrine reuptake.
Blocks voltage-dependent calcium channels thereby enhancing pregabalin activity.
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