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Cardiac & Anti-Diabetic

Home »  Products » Cardiac & Anti-Diabetic  » TENLIFAST TABS
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TENLIFAST  TABLETS

Teneligliptin Hydrobromide Hydrate 

eq. to Teneligliptin 20 mg 

INDICATIONS

Type 2 diabetes

Diabetic patients with cardiovascular disease

Elderly diabetic patients

Metformin intolerable patients

 

 

Diabetes if left unchecked can lead to...

Nephropathy

Retinopathy

Neuropathy

Heart Disease

 

A novel DPP-4 inhibitor with a preferable profile in terms of long-term efficacy and safety.

Effectively improves beta cell function and decreases insulin resistance.

Gives potent and sustained effects on glycemic control and reduces diabetic complications.

Shows significant improvement in lipids profiles along with improvement in blood glucose & HbA1c level.

Effectively Enhances adiponectin levels to regulate insulin sensitivity & energy homeostasis.

 

Benefits of Teneligliptin over other Glipins:

Provides strongest binding to DPP-4 enzymes as compared to other gliptins.

Normalizes daily blood glucose fluctuations by suppressing post prandial hyperglycemia at all three meals.

No dose adjustment is required in renal impairment.

Ensures stabilization of glucose fluctuations throughout the day in once due to long half life of 24.2 hours.

Teneligliptin 20mg once daily is more potent than voglibose 0.2mg t.i.d or vildagliptin 50mg qd.

Shows pleiotropic effects by improving vascular endothelial function within two weeks in diabetic patients with cardiac complications.

 

Pharmacokinetic profile of Teneligliptin

Parameters

Bioavailability - 63-85%

Tmax - 1.33h

Protein Binding - 78-80%

T 1/2 - 26.9hr

Clearance (%) - Faeces (46.5%) Urine(45.4%)

Drug-Drug interactions - No major clinically relevant drug- drug interactions.