ACORD – L Tablets

For that extra care…

 

COMPOSITION: Amlodipine 5 mg + Losartan Potassium 50 mg

  • Highly effective as antianginal and anti-hypertensive agent in patients with stable angina pectoris and mild to moderate hypertension.
  • Demonstrates 82% reduction in blood pressure with Amlodipine in comparison with 69% of Felodipine.
  • Highly efficient in preventing new coronary artery lesion formation and thereby efficiently controlling blood pressure.

INDICATIONS:

  • High blood pressure
  • Angina pectoris

Amlodipine

  • Class of medication: Calcium channel blockers
  • Amlodipine works by blocking the voltage-dependent L-type calcium channels, thereby inhibiting the initial influx of calcium.
  • Amlodipine has been shown to improve vascular endothelial function in hypertensive patients.
  • Amlodipine has good efficacy and safety, in addition to strong evidence from large randomized controlled trials for cardiovascular event reduction.

Losartan Potassium

  • Class of medication: Angiotensin receptor blockers (ARBs)
  • Has a duration of activity of at least 24hrs, with a good safety profile.
  • Losartan has wonderful clinical effectiveness in the treatment of essential hypertension
    and congestive heart failure.
  • It is a nonpeptide angiotensin II (AII) receptor antagonist; an important antihypertensive agent.
  • First of a new class of drugs to be introduced for clinical use in hypertension.

Combination

A randomized multicentre study says amlodipine/losartan therapy provides an effective and generally well-tolerated first-line therapy for reducing blood pressure in stage 2