ACTIWALK Gel

For Accelerated Pain Relief

  • Diclofenac Diethylamine B.P. 1.16% w/w eq. to Diclofenac sodium 1%w/w + Linseed Oil B.P. 3%w/w + Methyl salicylate I.P. 10%w/w +Menthol I.P. 5% w/w + Capsaicin USP 0.025%w/w+ Preservative Benzyl Alcohol I.P. 1%w/w

Topical nonsteroidal anti-inflammatory drug formulations produce a site-specific effect (ie, cyclo-oxygenase inhibition) while decreasing the systemic exposure that may lead to undesired effects in patients.

Topical preparations have a good safety profile, which might benefit the elderly and pediatric populations and those presenting with intolerance to traditional treatments

Actiwalk Gel / Roll-On is,

  • An analgesic non-steroidal anti-inflammatory non-invasive drug.
  • Topical applicative to reduce and manage chronic pain.

COMPOSITION

Diclofenac Diethylamine

  • Topical DDEA 1.16% gel is clinically proven to be effective and well-tolerated in acute and chronic musculoskeletal conditions.

ACTIWALK Gel

diclofenac DEA gel applied 4 times daily

has been shown to effectively relieve the pain of OA of the knee in a large, placebo-controlled study with well-accepted clinical pain measurements. Therefore diclofenac DEA gel

Personal non-commercial use only. The Journal of Rheumatology Copyright © 2005. All rights reserved.

 

can be recommended as first-line therapy for the treatment of the pain of OA of the knee diclofenac DEA gel applied 4 times daily has been shown to effectively relieve the pain of OA of the knee in a large, placebo-controlled study with well accepted clinical pain measurements. Therefore diclofenac DEA ge diclofenac DEA gel applied 4 times daily has been shown to effectively relieve the pain of OA of the knee in a large, placebo-controlled study with well accepted clinical pain measurements. Therefore diclofenac DEA g

  • With good tolerability DDEA 1.16% gel may be a preferable alternative to oral NSAIDs. 
  • Can be recommended as first-line therapy for the treatment of the pain of OA of the knee. 

Linseed oil

  • Proved to possess noticeable antiarthritic and immunomodulatory activity. 
  • Rich in α-linolenic acid, inhibits arachidonic acid (inflammatory mediators) induced inflammation. 
  • More effective in the improvement of symptoms and function of patients with mild to moderate carpal tunnel syndrome as compared with hand splint.

Methyl salicylate and Menthol 

  • Topical NSAID Methyl salicylate is documented as an option in the management of temporomandibular joint disorder (TMD) with a better safety profile and a non-invasive alternative to reduce their pain. 
  • Menthol-based topical analgesic was more effective than ice for decreasing delayed onset muscle soreness induced symptoms of pain in the elbow flexors. 
  • Significant pain relief from muscle strain following 8-hour application of a patch containing methyl salicylate and menthol compared to placebo in a randomized double blind trial.

 Capsaicin

  • 0.025% capsaicin cream as symptomatic therapy in patients with osteoarthritis (OA) pain reported a greater reduction of pain on the visual analog scale at 4 weeks.
  • Joint tenderness evaluated by palpation declined in capsaicin-treated patients. 

Benzyl alcohol 

  • Used as an antimicrobial preservative in many topical preparations.