Description

• A GABA analog, originally developed for the treatment of epilepsy, and currently widely used to relieve pain, especially neuropathic pain and major depressive disorders.

• An anticonvulsant that is used for preventing seizures by affecting chemicals and nerves in the body that are involved in the cause of seizures and some types of pain.

• Relieves the pain of postherpetic neuralgia by halting the formation of new synapses in the central nervous system

• Approved by the U.S. Food & Drug Administration in 1994 for use as an adjunctive medication to control partial seizures.

• In 2002, few indications were added; for treating postherpetic neuralgia, other painful neuropathies, and nerve-related pain.

• Prophylactic treatment with gabapentin was found to be associated with a significant reduction in the number of days with headache, use of acute medications, and pain intensity. 

• Prophylactic treatment with gabapentin was found to be associated with a significant reduction in the number of days with headache, use of acute medications, and pain intensity.