It reduces the synaptic release of several neurotransmitters, by binding to alpha2-delta subunits, and thus, reduces neuronal excitability and seizures.
Epilepsy Res. 2007 Feb, 73/21 137-50
Effective in reducing pain and improving sleep disturbances due to diabetic pain
Effectively manages neuropathic pain through inhibition of serotonin and norepinephrine reuptake.
Blocks voltage-dependent calcium channels thereby enhancing pregabalin activity.