Description

Camphor 

Drug class – Antitussive (anti-cough)

• Camphor is a natural product that has a counterirritant, rubefacient, and mild analgesic action, readily absorbed after inhalation (Baselt and Cravey 1990) derived from the wood of the Cinnamomum camphora L.

• Its nasal decongesting activity seems to be not purely mechanic but connected with the stimulation of cold receptors in the nose.

• The inhalation of camphor vapors increased the nasal sensation of airflow through the induction of cold sensation in the nose 

Chlorothymol 

Drug class – Antifungal agent

• Is a derivate of thymol which is an antifungal agent which is tested to be active against Candida albicans strains which cause human allergic airway diseases, such as asthma.

amphor, a natural product derived from the wood of the tree Cinnamomum camphora, has a  long history of use as anti-septic, analgesic, antipruritic, counterirritant and rubefacient (Hercogov 2005; Lynde et al. 2008). Its  success and wide medical use, especially in topical preparations, is connected to its mild local  anesthesizing effect and to the production of a circumscribed sensation of heat, together with its char-acteristic and penetrating odour  that is by most of people associated to the idea  of a strong and effective medicine 

Eucalyptol Oil

Drug class – Monoterpenoid

• Traditional medicine as an anti-inflammatory, analgesic, and antipyretic agent, and to treat flu, common cold, and nose bleeds.

• Eucalyptol was shown to inhibit LTB4 and PGE2 which regulate inflammatory processes, both pathways of AA-metabolism in patients with bronchial asthma.

Menthol

Drug class – Counterirritant

• Menthol as a plant extract of peppermint, induces the sensation of cooling by activating gene TRPM8 (menthol receptor).

• Nishino et al. found that nasal inhalation of l-menthol reduced the sensation of respiratory discomfort associated with loaded breathing.

• Used as a treatment for the relief of nasal congestion associated with rhinitis and its effects on the drive to breathe and symptomatic relief of dyspnea.