Drug class – Antitussive (anti-cough)
- Camphor is a natural product that has a counterirritant, rubefacient, and mild analgesic action, readily absorbed after inhalation (Baselt and Cravey 1990) derived from the wood of the Cinnamomum camphora L.
- Its nasal decongesting activity seems to be not purely mechanic but connected with the stimulation of cold receptors in the nose.
- The inhalation of camphor vapors increased the nasal sensation of airflow through the induction of cold sensation in the nose
Drug class – Antifungal agent
- Is a derivate of thymol which is an antifungal agent which is tested to be active against Candida albicans strains which cause human allergic airway diseases, such as asthma.
amphor, a natural product derived from the wood of the tree Cinnamomum camphora, has a long history of use as anti-septic, analgesic, antipruritic, counterirritant and rubefacient (Hercogov 2005; Lynde et al. 2008). Its success and wide medical use, especially in topical preparations, is connected to its mild local anesthesizing effect and to the production of a circumscribed sensation of heat, together with its char-acteristic and penetrating odour that is by most of people associated to the idea of a strong and effective medicine
Drug class – Monoterpenoid
- Traditional medicine as an anti-inflammatory, analgesic, and antipyretic agent, and to treat flu, common cold, and nose bleeds.
- Eucalyptol was shown to inhibit LTB4 and PGE2 which regulate inflammatory processes, both pathways of AA-metabolism in patients with bronchial asthma.
Drug class – Counterirritant
- Menthol as a plant extract of peppermint, induces the sensation of cooling by activating gene TRPM8 (menthol receptor).
- Nishino et al. found that nasal inhalation of l-menthol reduced the sensation of respiratory discomfort associated with loaded breathing.
- Used as a treatment for the relief of nasal congestion associated with rhinitis and its effects on the drive to breathe and symptomatic relief of dyspnea.