FERTOXID-F- Berberine Hydrochloride, Myo-Inositol, D-Chiro Inositol, L- Methylfolate, Melatonin, Grape Seed Extract, Vitamin D3, DHA & Chromium Picolinate Tablets

PRODUCT SYNOPSIS

Fertoxid-F is a specialized nutraceutical to strengthen your fight against PCOS and infertility. It contains a wealth of nutrients, including vitamin D3, chromium picolinate, myo-inositol, L-methylfolate, melatonin, and grape seed extract. This powerful combination is intended to promote hormonal balance, which may aid in increasing pregnancy rates and offer many more great benefits to suppress the negative effects of pregnancy.

PHARMACOLOGICAL HEALTH BENEFITS

Berberine

It is a phytogenous alkaloid that has a wide range of therapeutic properties, including anti-inflammatory, antioxidant, antitumor, antibacterial, hepatoprotective, hypolipidemic, and hypoglycemic properties. Natural sources of berberine with the highest concentration are Coptidis rhizoma and barberry.

According to experts, berberine (BBR) seems to be a powerful tool as an insulin-sensitizing agent. It improves the ovulation rate and live birth rate by controlling androgen levels, decreasing fasting plasma glucose and insulin levels, and lowering insulin resistance. It may offer positive pregnancy outcomes in polycystic ovarian syndrome (PCOS)-afflicted insulin-resistant women.²

Myoinositol and D-Chiro Inositol

A natural polyol, the most abundant among the nine possible structural isomers present in living organisms. And D-chiro inositol is its most relevant epimer.

These alleviate the symptoms of PCOS and similar disorders. Increases the pregnancy rate by reducing ovarian hyperstimulation syndrome and improving oocyte quality.³

L-methyl folate

It lowers the incidence of anemia. Regulates homocysteine metabolism and lowers adverse pregnancy outcomes. Known to reduce the risk of vascular disease and prevent neural tube defects. ⁴ Methyl-folate can be a good substitute for folic acid in supplements for reducing the risk of vascular disease and preventing neural tube defects. ⁵

Melatonin

An endogenous lipid-soluble hormone that regulates the circadian cycle. It is a highly effective direct free-radical scavenger and indirect antioxidant. Acts as a cytoprotective agent that counteracts neonatal pathologies (asphyxia, respiratory distress syndrome, sepsis, etc.) ⁶

Grape seed extract (GSE)

A complex mixture of polyphenols, primarily containing catechin polymers. Shown to have significant anti-oxidative stress potential, manage maternal hypertension, and promote cardiovascular protection during pregnancy. ⁷

Vitamin D

A fat-soluble vitamin with a lipophilic nature. May help increase the chances of successful reproduction in infertile patients who are deficient. It is beneficial for fetal skeletal growth, regulation of cell differentiation and apoptosis, the immune system, and brain development. It also reduces the risk of preeclampsia. ⁸

DHA (Docosahexaenoic acid)

A long-chain PUFA, a member of the omega-3 fatty acid family. May aid in the reduction of early preterm birth. ⁹

Chromium Picolinate

Exerts beneficial effects on metabolic abnormalities among women suffering from PCOS. Also manages hyperinsulinemia and hyperandrogenemia. ¹⁰

INDICATIONS

Metabolic syndromes like PCOS
Fertility issues
Endometriosis
Hyperinsulinemia and hyperandrogenemia

Uterine defects
Gestational Diabetes
Maternal hypertension
Reduction of the risk of preterm birth

ROUTE OF APPLICATION

Oral

RECOMMENDED DOSAGE

As recommended by a healthcare professional.

SIDE/ADVERSE EFFECTS

Not Applicable

CONCLUSION

Fertoxid-F is a nutraceutical formulated with plant-sourced elements supported by science to enhance women’s fertility and a healthy pregnancy. It offers a good therapeutic alternative for managing negative pregnancy outcomes as they provide pharmacologically beneficial effects that may aid women of reproductive age who are facing fertility issues like PCOS hormonal imbalance and several other reproductive health concerns.

REFERENCES

1. Life (Basel). 2023 Jan; 13(1): 125.
2. Cureus. 2022 Oct; 14[10]: e30351.
3. Gynecol Endocrinol. 2022 Apr;38(4):275-278.
4. Am J Clin Nutr. 2004 Mar;79(3):473-8.
5. Rev Obstet Gynecol. 2011; 4(3-4): 126–127.
6. J Matern Fetal Neonatal Med. 2012 Mar;25(3):207-21.
7. Front Physiol. 2020; 11: 588000.
8. Reprod Biol Endocrinol. 2023; 21:17.
9. Am J Clin Nutr 2019;109:1380–1392.
10. Iran J Reprod Med. 2013 Aug; 11(8): 611–618.
11. Int J Reprod Biomed. 2019 Dec; 17(12): 865–882.
12. Front. Public Health, 17 August 2022, Sec. Public Health and Nutrition, Volume 10 - 2022

FAQs

Where is Berberine HCl sourced from?

Berberine, a phytogenous alkaloid, is extracted from various vegetable species such as Barberry, Meadow rue, Celandine, Goldenseal, and Chinese herbs like Coptidis rhizoma, Phellodendron chinense, Phellodendron amurense.

L-Methylfolate is natural / organic?

L-methylfolate is the primary active form of folate, which you can take as a supplement to raise your body’s low folate levels. Legumes, cruciferous vegetables, and dark green leafy vegetables all contain folate, which is the natural form of vitamin B9.

Does inositol improve the fertility rate?

It has been demonstrated that inositol supplementation enhances egg quality and increases the chances of fertilization.

How does Melatonin aid fertility?

Melatonin exerts protective effects against metabolic and reproductive abnormalities in PCOS patients. Its scavenging action is crucial during ovulation, as it quenches reactive oxygen species (ROS) and reactive nitrogen species (RNS), protecting the gynecological cavity and oocyte. ¹¹

Does DHA aid in fertility?

Studies have shown that DHA is a protective factor against infertility. According to research, supplementing with omega-3 fatty acids, which are a type of DHA, might offer a practical and affordable way to enhance fertility. ¹²