A Reason to Smile in Osteoarthritis


  • Diacerein IP 50mg + Glucosamine USP 750mg + Methyl Sulfonyl methane 250mg


  • Drug class:  Anthraquinone
  • Improved cartilage lesions and consistently reduced cartilage loss in the experimental hip chondrolysis model.
  • Induced an increase in bone mineral density and shown to delay arthritis secondary to meniscectomy
  • Osteoarthritis Research Society International (OARSI) indicated that diacerein had a greater efficacy on pain reduction in OA than paracetamol.


  • Drug class:  Amino sugar, Hexosamines
  • At sufficiently high doses, glucosamine sulfate possesses a clinically relevant effect on OA pain.
  • More effective than placebo in reducing the rate of joint space narrowing in patients with knee OA.  
  • May be effective in the primary prevention of OA in sportsmen.

Methyl Sulfonyl methane (MSM)

  • Drug class: Sulfa drugs
  • MSM in patients with OA of the knee, showed an improvement in pain and physical function. 
  • Used by the body to maintain and repair connective tissue. 


  • A combination of nutraceuticals Glucosamine, diacerein, and methyl-sulfonyl-methane can effectively treat OA by repairing the damaged articular cartilage.