NIMUSTAR-100 DT Tablets

A Functional Drug from Rising Generation for Fruitful Therapy

COMPOSITION – Nimesulide 100 mg



Both cyclooxygenase COX-1 and COX-2 in our body produce prostaglandins that promote inflammation, pain, and fever.

  • However, only COX-1 produces prostaglandins that activate platelets and protect the stomach and intestinal lining.  The blockage of COX-1 in consequence causes the adverse effects of NSAIDs. 
  • When the COX-1 enzyme is blocked, inflammation is reduced, but the protection of the lining of the stomach also is lost; this may lead to stomach upset as well as ulceration.
  • And COX-2 is responsible for the most inflammatory symptoms, such as pain, edema, fever, and increase in vessel permeability. 

So the selective inhibitors of COX-2 would be much more safe drugs, compared with the classical NSAIDs in the treatment of inflammatory diseases.  


  • Drug class: Sulphonanilide
  • Not only inhibits more selectively the activity of COX-2 but also some other properties that increase its anti-inflammatory and analgesic function.
  • Belongs to the new generation of NSAIDs, unique as it contains sulphonanilide group. 
  • Nimesulide (unlike most other NSAIDs) in the recommended doses appears to be well tolerated in aspirin-sensitive asthmatic patients. 
  • An effective and well-tolerated alternative to other NSAIDs for short-term treatment of pain and inflammation of osteoarthritis and various other causes. Drugs.


  • At the recommended dosage of 100 mg twice a day nimesulide is as effective an analgesic and anti-inflammatory agent as classical NSAIDs.