Description

Silymarin

• A mixture of flavonolignans and minor polyphenolic compounds derived from milk thistle, exerts antioxidant, anti-inflammatory, & antifibrotic effects.

 

• Acts as a free radical scavenger and modulates enzymes associated with the development of cellular damage, fibrosis, and cirrhosis.

L-Glutathione

• Glutathione (GSH) is an antioxidant produced in cells.

• GSH administration is a promising strategy to recover oxidative stress-induced liver damages in alcoholic and non-alcoholic liver diseases.

N-Acetyl Cysteine

• N-acetyl cysteine (NAC) is the acetylated form of the amino acid L- cysteine.

• Has a well-established role in acetaminophen-induced & non-acetaminophen-induced liver failure also reported to reduce mortality in these patients. 

• Increases glutathione & nitric oxide levels hence exerting antioxidant effect and vasodilatory effect.

L-carnitine & L-ornithine

• L-carnitine plays a key role in maintaining liver function, by its effect on lipid metabolism.
• It transports fatty acids into the mitochondria for oxidation, and 
• Buffers excess acetyl-CoA away from the mitochondria.

• L-ornithine, a non-protein amino acid;
• Improves hepatic function by increasing blood levels in the liver. 
• Reduces plasma ammonia, an important therapeutic target for hyperammonemia in liver failure.

Choline & Antioxidants & Micronutrient  

• Choline is an essential nutrient for the export of triglycerides from the liver.

• Potent hydro-soluble antioxidants like vitamin C can help block the development of steatosis and Nonalcoholic Fatty Liver Disease.