H.Pylori is a prevalent infection in India with as many as nearly 60% reporting positive for it.
H. pylori infection and NSAID/aspirin use show a higher prevalence of Peptic ulcer disease and ulcer bleeding in the elderly.
H. pylori-positive NSAID users have an almost two-fold increased risk of peptic ulcer bleeding compared to NSAID users without H. pylori.
So, triple drug therapy of a PPI + Clarithromycin + Amoxycillin is a safe approach.
- One-week triple therapy is a first-line anti-H. pylori treatment.1
- Effective and well-tolerated therapeutic approach with H.Pylori eradication rate of 94%.
- Has a low rate of side effects & high rates of patient compliance.2
- Useful in elderly patients with dyspeptic symptoms or reflux diseases.3
Drug Class: Proton Pump Inhibitors
- Selective PPI used in the treatment of stomach ulcers.
- GERD and other acidity-related disorders.
- Decreases the acid production in the stomach and helps promote healing of ulcers
Drug Class: Macrolide antibiotics
- An acid-stable, better absorbed & widely used component of anti-H pylori regimen.
- High antimicrobial activity & fewer gastrointestinal adverse effects.4
Drug Class: Penicillin-like antibiotics.
- In combination with clarithromycin treats ulcers caused by H.pylori infection.
- Inhibits the production of the bacterial cell wall.