Effective Combination to Tackle H.Pylori

COMPOSITION: Pantoprazole 40mg + Clarithromycin 500mg + Amoxycillin 750mg


H.Pylori is a prevalent infection in India with as many as nearly 60% reporting positive for it. 

H. pylori infection and NSAID/aspirin use show a higher prevalence of Peptic ulcer disease and ulcer bleeding in the elderly.

H. pylori-positive NSAID users have an almost two-fold increased risk of peptic ulcer bleeding compared to NSAID users without H. pylori. 

So, triple drug therapy of a PPI + Clarithromycin + Amoxycillin is a safe approach.

  • One-week triple therapy is a first-line anti-H. pylori treatment.1
  • Effective and well-tolerated therapeutic approach with H.Pylori eradication rate of 94%.
  • Has a low rate of side effects & high rates of patient compliance.2
  • Useful in elderly patients with dyspeptic symptoms or reflux diseases.3


Drug Class: Proton Pump Inhibitors

  • Selective PPI used in the treatment of stomach ulcers.
  • GERD and other acidity-related disorders.
  • Decreases the acid production in the stomach and helps promote healing of ulcers


Drug Class: Macrolide antibiotics

  • An acid-stable, better absorbed & widely used component of anti-H pylori regimen.
  • High antimicrobial activity & fewer gastrointestinal adverse effects.4


Drug Class: Penicillin-like antibiotics.

  • In combination with clarithromycin treats ulcers caused by H.pylori infection.
  • Inhibits the production of the bacterial cell wall.