Strong Combination for Powerful and Prolonged Relief

COMPOSITION: Pantoprazole Sodium 40mg (As Enteric-coated Pellets) + Levosulpiride IP 75mg (As Sustained Release Pellets) 



Drug Class: Proton Pump Inhibitors

  • A proton pump inhibitor drug effective for both acute and long-term treatment with excellent control of erosion and ulceration of the esophagus caused by GERD. 
  • It is well tolerated even for long-term therapy with optimal tolerability and its pharmacokinetics are found to be independent of patient age.
  • Shown to have minimal interactions with other drugs because of a lower affinity for cytochrome P450 than older PPIs.
  • Produces superior symptomatic remission rates and clinical efficacy compared with an H2 antagonist (like ranitidine).


Drug Class: A prokinetic agent of the benzamide class.

  • Levosulpiride, a levorotatory enantiomer of sulpiride is an effective antipsychotic and a prokinetic agent.
  • Improves overall symptoms of reflux esophagitis rapidly and effectively, by increasing lower esophageal sphincter pressure.
  • Shown to increase interdigestive migrating motor complexes in the gastric antrum, promoting the propagation of motor waves from the stomach into the duodenum. 
  • Gallbladder and gastric emptying time as well as intestinal transit time were shortened.
  • Due to its antiemetic property it ameliorated nausea & vomiting in postoperative conditions and during cancer chemotherapy more effectively than metoclopramide.