RECICARD-T Tablets

The Combat Combination

 

COMPOSITION: Cilnidipine 10 mg + Telmisartan IP 40 mg 

  • Minimizes vascular damage, angioedema and improves patient adherence leading to long term BP control.
  • Cardioprotective, dual mode of action reduces the risk of cardiovascular diseases.
  • An open-label study done in India proves that a combination of telmisartan and chlorthalidone is more effective than telmisartan and hydrochlorothiazide.
  • Telmisartan owns a greater anti-hypertensive effect than ramipril, enalapril and perindopril along with end-organ protection beyond BP control.
  • Reduces the need for dose escalation, improves arterial stiffness and offers renoprotection.

INDICATIONS:

  • Hypertension
  • Cardiovascular Disorders
  • Arterial Stiffness
  • Angioedema

Cilnidipine 

  • Class of medications: Calcium blockers
  • Centrally acting as dihydropyridine calcium antagonist, improves the ambulatory BP & HR profile by significant suppression of LVH in hypertensive CKD patients. 
  • Reduce urinary proteinuria than amlodipine, in protein-uric and hypertensive patients treated with renin-angiotensin blockades. 
  • Significantly decreases urinary albumin excretion without affecting serum creatinine concentration in hypertensive patients as compared to ACE inhibitor benazepril. 

Telmisartan

  • Class of medications: Angiotensin II receptor antagonists
  • Newer angiotensin receptor blocker, very useful for the management of patients with mild-to-moderate hypertension.
  • An important alternative as the first-line treatment of hypertension. 
  • Produces greater reductions in both systolic blood pressure (SBP) & diastolic blood pressure (DBP) when compared with losartan. 
  • Exert its PPARgamma enhancing activity clinically in obese or overweight type 2 diabetic patients as compared to candesartan.

COMBINATION

  • The combination therapy was more effective in reducing BP than either drug in monotherapy without affecting glucose homeostasis. 
  • Combination therapy with Cilnidipine & Telmisartan is more effective than treatment with Cilnidipine & Telmisartan alone & exhibits additive protective effects on renal & cardiac organs. 
  • Cilnidipine & telmisartan, synergistically decreased plasma aldosterone concentrations and pulse wave velocity for preventing vascular complications.