Description

Sodium Monofluorophosphate (Na2PO3F)

Drug Class: Inorganic salt

• Reduce the ability of bacteria to make acids

• Dentifrices formulated with sodium monofluorophosphate provide an equivalent level of anticaries efficacy as to those formulated with sodium fluoride.

• Use of sodium monofluorophosphate dentifrice was as effective in reducing caries as twice annual, professionally applied, treatments of an acidulated phospho-fluoride gel.

• After 3 years of uncontrolled use, the number of new DMF surfaces is smaller in children using Na2PO3F toothpaste and the caries-inhibiting effect was statistically significant compared to the placebo groups.

(Note: Decayed, Missing, Filled (DMF) index is the key measure of caries experience in dental epidemiology.)