Total Relief from Muscle- pain

COMPOSITION – Aceclofenac Sodium 100 mg + Tizanidine 2 mg




  • Drug class: BCS Class II
  • An NSAID with anti-inflammatory and analgesic properties reduces pain & inflammation; effective in improving functional capacity in chronic pain conditions. 
  • A potent COX-2 inhibitor with a well-established efficacy and tolerability profile in patients with musculoskeletal disorders.
  • Generally well tolerated, with a safety profile consistent with that expected of NSAIDs.


  • Drug class: Alpha-2-adrenergic agonists (Skeletal muscle relaxants)
  • A centrally acting alpha-2-adrenergic agonist that is used as a muscle relaxant with sedative, anxiolytic, and analgesic properties. 

[Note: α-adrenergic agonists play a crucial role in regulating BP by stimulating alpha adrenergic receptors.]

  • Generates less fluctuation in blood pressure and provides cardiovascular stability and has a shorter duration of action unlike other α-2 agonists like clonidine. 
  • Reduces spasticity by increasing pre-synaptic inhibition of neurons; showed significant reduction in pain and tissue tenderness and improved the quality of sleep in myofascial pain.

Aceclofenac–tizanidine Combination

  • The combination was more effective than aceclofenac alone and had a favorable safety profile in the treatment of acute low back pain.