URIFINE-T Tablet

Keeps Urinary Tract Fit & Fine

COMPOSITION: Tamsulosin HCI IP 0.4mg + Finasteride IP 5mg

The combination of Tamsulosin HCI – Finasteride is used for the treatment of lower urinary tract symptoms associated with benign prostatic hyperplasia.

Tamsulosin

Drug class: Alpha blockers

  • A selective alpha-1 adrenoceptor blocker, which blocks the adrenoceptors leading to the relaxation of smooth muscles in the bladder neck, and prostate to relax.
  • Highly efficacious in patients with lower urinary tract symptoms due to benign prostatic enlargement.
  • Considered as a safe and effective medical expulsive therapy choice for ureteral stones.
  • Tamsulosin was better than placebo at improving international prostate symptom score (IPSS) and maximum flow rate (MFR).
  • Blocks the effects of adrenalin on the muscle cells and causes the muscles to relax and thus resulting in a decrease in obstruction to the flow of urine.
  • Beneficial in terms of the reduced number of ureteral colic episodes and the severity of pain in the patients.

Finasteride

Drug class:  5-alpha reductase inhibitors

  • A competitive inhibitor of the 5-alpha reductase, an enzyme that converts testosterone to dihydrotestosterone (DHT).
  • Conversion of testosterone to DHT by 5-alpha reductase is essential for prostatic hyperplasia.
  • Inhibits prostatic enlargement by reducing circulating and intraprostatic dihydrotestosterone.
  • Reduce the risk of the need for surgery including transurethral resection of the prostate (TURP) and prostatectomy.
  • Substantially reduces the risk of incident clinical BPH in healthy older men.