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ZIVALIO-M 500ER (Dapagliflozin 10mg + Metformin HCL IP 500mg) Tablets: Uses, MOA, Benefits, and Recommended Dosage


ZIVALIO-M 500ER Tablets: Optimizing Glycemic Control

ZIVALIO-M 500ER Tablets are a combination medication containing Dapagliflozin 10mg and Metformin Hydrochloride IP 500mg, offering a comprehensive approach to managing type 2 diabetes. This formulation leverages the synergistic effects of both components to effectively regulate blood sugar levels and improve overall metabolic health.


ZIVALIO-M 500ER Tablets provide a dual-action approach to diabetes management, targeting both glucose reabsorption in the kidneys and hepatic glucose production. By combining Dapagliflozin, a sodium-glucose co-transporter 2 (SGLT2) inhibitor, with Metformin, a biguanide antidiabetic agent, this medication addresses multiple facets of the disease.

Mechanism of Action (MOA):

Dapagliflozin inhibits SGLT2 in the proximal tubules of the kidneys, thereby reducing renal glucose reabsorption and promoting urinary glucose excretion. Metformin primarily acts by decreasing hepatic glucose production, enhancing insulin sensitivity, and improving peripheral glucose uptake.

Uses and Benefits:

ZIVALIO-M 500ER Tablets are indicated for the management of type 2 diabetes mellitus to improve glycemic control in adults. This combination helps lower blood glucose levels, reduce the risk of cardiovascular events, and may lead to weight loss due to the excretion of excess glucose in the urine.

Recommended Dosage:

The recommended dosage of ZIVALIO-M 500ER Tablets is typically one tablet taken orally once daily with meals. Dosage adjustments may be necessary based on individual patient needs and response to treatment. It is important to follow the healthcare provider’s instructions regarding dosing.

Adverse Reactions and Precautions:

Common adverse effects associated with ZIVALIO-M 500ER Tablets may include urinary tract infections, genital mycotic infections, and gastrointestinal discomfort. Patients should be monitored for signs of dehydration and hypoglycemia. It is contraindicated in patients with severe renal impairment, hepatic impairment, and type 1 diabetes.


ZIVALIO-M 500ER Tablets offer a valuable treatment option for individuals with type 2 diabetes, providing effective glycemic control and potential cardiovascular benefits. This combination medication represents a significant advancement in diabetes management, underscoring the importance of comprehensive therapy approaches.

ZIVALIO-M 500ER Tablets: Learn More About Optimal Diabetes Care

Explore the benefits of ZIVALIO-M 500ER Tablets in achieving better blood sugar control and overall metabolic health. Consult your healthcare provider to determine if this medication is suitable for your diabetes management plan.

Related Combinations:

Explore our comprehensive range of diabetes management solutions at Invision Medi Sciences.

ZIVALIO-M 500ER Tablets: Empowering Your Journey to Better Diabetes Management


What is the recommended dosage for ZIVALIO-M 500ER Tablets?

The typical recommended dosage is one tablet taken orally once daily with meals. However, individual dosage may vary, so it’s important to follow your healthcare provider’s instructions.

What are the common side effects of ZIVALIO-M 500ER Tablets?

Common side effects may include urinary tract infections, genital mycotic infections, and gastrointestinal discomfort. Be sure to consult your healthcare provider if you experience any adverse reactions.

Can ZIVALIO-M 500ER Tablets be used alone or in combination with other diabetes medications?

ZIVALIO-M 500ER Tablets are typically used as a standalone treatment for type 2 diabetes. However, your healthcare provider may adjust your treatment plan as needed based on your individual condition.

How long does it take to see results with ZIVALIO-M 500ER Tablets?

The timeframe for experiencing noticeable results may vary from person to person. It’s essential to continue taking the medication as prescribed and monitor your blood sugar levels regularly.

Are there any special precautions or considerations when taking ZIVALIO-M 500ER Tablets?

Patients with severe renal impairment, hepatic impairment, or type 1 diabetes should avoid using ZIVALIO-M 500ER Tablets. Additionally, it’s essential to stay hydrated and monitor for signs of hypoglycemia while taking this medication. Always consult your healthcare provider for personalized advice.

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