Cefoperazone-tazobactam is effective & safe in the treatment of bacterial infections caused by susceptible organisms



Sterile Cefoperazone Sodium IP 1000 mg + Tazobactam Sodium 125 mg


  • Lower Respiratory tract infections
  • Skin and Skin structure infections
  • Urinary Tract infections (complicated and uncomplicated)
  • Intra-Abdominal infections
  • Meningitis
  • Surgical prophylaxis
  • Gynecological Infections
  • Post Operative infections




  • A parenteral semi-synthetic broad-spectrum cephalosporin with a good tolerability profile
  • Excellent susceptibility against most Gram positive & Gram negative aerobic & anaerobic pathogens with overall bacteriological eradication at least 85%
  •  Inhibits the biosynthesis of cell wall mucopeptides & exhibits minimal immunosuppressant activity.
  • Safe & effective in the therapy of acute bacterial lower respiratory tract infections with 92% clinical efficacy.
  •  Effective & safe alternative in Clindamycin and gentamycin treatment of intra-abdominal infections


  • A potent, highly specific inhibitor of a wide variety of beta-lactamases produced by common gram-negative and gram-positive aerobes and anaerobes.
  •  Forms a protein complex with beta-lactamases and irreversibly blocks their destructive hydrolytic activity.
  • The study corroborates the efficacy of the beta-lactamase inhibitor tazobactam in improving the spectrum of activity and efficacy of cefoperazone
  • Generally acts as an irreversible inhibitor and inactivates both plasmid and chromosomally mediated beta-lactamases