CEFDINEX-TZ Injection

Safer Surer & Faster

COMPOSITION: Cefoperazone 1000 mg + Tazobactam Sodium 125 mg

CEFDINEX-TZ Injection

Cefoperazone (Cephalosporin antibiotics)

  • A parenteral semi-synthetic broad-spectrum cephalosporin with a good tolerability profile.
  • Excellent susceptibility against most Gram-positive & Gram-negative aerobic & anaerobic pathogens with overall bacteriological eradication of at least 85%.
  • Inhibits the biosynthesis of cell wall mucopeptides & exhibits minimal immunosuppressant activity.
  • Safe & effective in the therapy of acute bacterial lower respiratory tract infections with 92% clinical efficacy.
  • Effective & safe alternative in Clindamycin & Gentamycin treatment of intraabdominal infections.

Tazobactam (Beta-lactamase inhibitor)

  • A potent, highly specific inhibitor of a wide variety of beta-lactamases produced by common gram-negative and gram-positive aerobes and anaerobes.
  • Forms a protein complex with beta-lactamases and irreversibly blocks their destructive hydrolytic activity.
  • The study corroborates the efficacy of the beta-lactamase inhibitor tazobactam in improving the spectrum of activity and efficacy of cefoperazone.
  • Generally acts as an irreversible inhibitor and inactivates both plasmid and chromosomally mediated beta-lactamases.

COMBINATION

  • Cefoperazone-tazobactam is effective & safe in the treatment of bacterial infections caused by susceptible organisms.