THROMBONEX – 10/20 Tablets

Effective, Convenient & Safe Anticoagulant

Rivaroxaban 10mg/20mg

  • An oral oxazolidinone-based anticoagulant agent.
  • It inhibits not only free factor Xa with high selectivity but also prothrombinase bound and clot-associated factor Xa in a concentration-dependent manner.
  • It is a potent, selective direct inhibitor of factor Xa that is used in the prevention of venous thromboembolism (VTE) in adult patients after total hip replacement (THR) or total knee replacement (TKR) surgery.
  • For a 10 mg dose, the oral bioavailability of Rivaroxaban is high (80–100%) and is not affected by food intake.
  • The drug is metabolized to inactive metabolites in liver, half of which is excreted by kidneys and other half is excreted via faecal route.