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ZITANEO-M500 SR [Sitagliptin 50mg + Metformin Hcl 500mg (SR)] Tablets: Uses, MOA, Benefits, and Recommended Dosage

ZITANEO-M500 SR

Introduction:

ZITANEO-M-500SR tablets are a combination medication containing Sitagliptin and Metformin Hydrochloride. This formulation is designed to help manage blood sugar levels in individuals with type 2 diabetes mellitus. By combining two distinct mechanisms of action, ZITANEO-M-500SR tablets offer comprehensive glycemic control.

Composition and Mechanism of Action (MOA):

Each ZITANEO-M-500SR tablet contains Sitagliptin (50mg) and Metformin Hydrochloride (500mg) in a sustained-release formulation. Sitagliptin belongs to the class of dipeptidyl peptidase-4 (DPP-4) inhibitors, which work by increasing insulin secretion and decreasing glucagon levels in response to meals, thereby lowering blood sugar levels. Metformin, on the other hand, is a biguanide that reduces hepatic glucose production, enhances peripheral glucose uptake, and improves insulin sensitivity.

Uses and Benefits:

ZITANEO-M-500SR tablets are indicated for the treatment of type 2 diabetes mellitus to improve glycemic control. By targeting multiple pathways involved in glucose metabolism, this combination medication helps regulate blood sugar levels, thereby reducing the risk of diabetic complications such as cardiovascular disease, neuropathy, and nephropathy. Additionally, ZITANEO-M-500SR tablets may also contribute to weight management and lipid profile improvement.

Recommended Dosage:

The recommended dosage of ZITANEO-M-500SR tablets should be individualized based on the patient’s glycemic status and tolerance. Typically, the usual starting dose is one tablet taken orally once daily with meals. Dosage adjustments may be necessary depending on the patient’s response, renal function, and other factors. It is important to follow the prescribing healthcare provider’s instructions regarding dosage and administration.

Adverse Reactions and Precautions:

Common adverse reactions associated with ZITANEO-M-500SR tablets may include gastrointestinal symptoms such as nausea, diarrhea, and abdominal discomfort. Rare but serious side effects may include lactic acidosis, allergic reactions, and pancreatitis. Patients with renal impairment, hepatic dysfunction, or other significant comorbidities should use caution when taking this medication. Regular monitoring of renal function, liver function, and blood glucose levels is recommended during therapy.

Conclusion:

ZITANEO-M-500SR tablets offer a convenient and effective treatment option for individuals with type 2 diabetes mellitus. By combining Sitagliptin and Metformin in a sustained-release formulation, this medication provides comprehensive glycemic control while minimizing the risk of hypoglycemia and other adverse effects. However, it is essential to use ZITANEO-M-500SR tablets under the supervision of a healthcare professional and adhere to the prescribed dosage regimen for optimal therapeutic outcomes.

Related Combinations:

Explore other facets of diabetes care with our related combination:

Comprehensive Glycemic Control with ZITANEO-M-500SR Tablets – Your Partner in Diabetes Management.

FAQs


What is the recommended dosage for ZITANEO-M-500SR tablets?

The recommended dosage of ZITANEO-M-500SR tablets should be individualized based on the patient’s glycemic status and tolerance. Typically, the usual starting dose is one tablet taken orally once daily with meals. Dosage adjustments may be necessary depending on the patient’s response, renal function, and other factors.

What are the common side effects of ZITANEO-M-500SR tablets?

Common side effects of ZITANEO-M-500SR tablets may include gastrointestinal symptoms such as nausea, diarrhea, and abdominal discomfort. It is essential to consult a healthcare provider if these side effects persist or worsen.

Can ZITANEO-M-500SR tablets be used in patients with renal impairment?

Patients with renal impairment should use caution when taking ZITANEO-M-500SR tablets. Dosage adjustments may be necessary based on the degree of renal dysfunction. It is important to consult a healthcare provider for proper guidance in such cases.

How does ZITANEO-M-500SR help in managing type 2 diabetes?

ZITANEO-M-500SR tablets work by combining the effects of Sitagliptin and Metformin Hydrochloride. Sitagliptin increases insulin secretion and decreases glucagon levels, while Metformin reduces hepatic glucose production and enhances peripheral glucose uptake, resulting in improved glycemic control.

Are there any special precautions to consider when taking ZITANEO-M-500SR tablets?

Patients with hepatic dysfunction, significant comorbidities, or a history of allergic reactions to any component of ZITANEO-M-500SR tablets should use caution when taking this medication. Regular monitoring of renal function, liver function, and blood glucose levels is recommended during therapy. It is essential to follow the prescribing healthcare provider’s instructions and report any unusual symptoms or side effects promptly.

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