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PREGANERVE-N (Pregabalin 75mg + Nortriptyline 10mg) Tablets: Uses, MOA, Benefits, and Recommended Dosage

PREGANERVE-N

Introduction:

PREGANERVE-N tablet is a combination medication that blends the potent analgesic properties of Pregabalin with the antidepressant effects of Nortriptyline. This unique formulation offers a comprehensive approach to managing neuropathic pain conditions, providing relief and improving overall quality of life for patients.\

Composition

Each PREGANERVE-N tablet contains Pregabalin 75mg and Nortriptyline 10mg. These active ingredients work synergistically to target neuropathic pain through different mechanisms of action, offering enhanced efficacy compared to individual therapies.

Mechanism of Action (MOA):

Pregabalin binds to calcium channels in the central nervous system, reducing the release of neurotransmitters involved in pain transmission. Nortriptyline, a tricyclic antidepressant, inhibits the reuptake of serotonin and norepinephrine, exerting analgesic effects by modulating pain perception pathways.

Uses and Benefits:

PREGANERVE-N tablet is indicated for the management of neuropathic pain associated with diabetic neuropathy, postherpetic neuralgia, and fibromyalgia. By addressing both the sensory and emotional components of pain, it provides significant relief and improves functional outcomes for patients.

Recommended Dosage:

The recommended dosage of PREGANERVE-N tablet should be determined by a healthcare professional based on individual patient characteristics and the severity of symptoms. It is typically initiated at a low dose and titrated gradually to achieve optimal pain control while minimizing side effects.

Adverse Reactions and Precautions:

Common side effects of PREGANERVE-N tablet may include dizziness, drowsiness, dry mouth, and constipation. Patients should be monitored for signs of worsening depression or suicidal thoughts, especially during the initial phase of treatment. Caution is advised when driving or operating machinery due to the potential for impaired cognitive function.

Conclusion:

PREGANERVE-N tablet offers a valuable therapeutic option for individuals suffering from neuropathic pain conditions. By combining the complementary mechanisms of Pregabalin and Nortriptyline, it addresses the multifaceted nature of neuropathic pain, providing effective relief and improving overall patient outcomes.

Related Combinations:

Explore our comprehensive range of diabetes management solutions at Invision Medi Sciences.

PREGANERVE-N: Dual Relief for Neuropathic Pain

FAQs


What is the recommended dosage of PREGANERVE-N tablet?

The dosage of PREGANERVE-N should be determined by a healthcare professional based on individual patient characteristics and the severity of symptoms. It is typically initiated at a low dose and titrated gradually to achieve optimal pain control while minimizing side effects.

How does PREGANERVE-N provide relief from neuropathic pain?

PREGANERVE-N combines the analgesic properties of Pregabalin with the antidepressant effects of Nortriptyline. Pregabalin reduces the release of pain neurotransmitters, while Nortriptyline inhibits their reuptake, providing comprehensive relief from neuropathic pain.

What are the common side effects of PREGANERVE-N tablet?

Common side effects may include dizziness, drowsiness, dry mouth, and constipation. Patients should be monitored for signs of worsening depression or suicidal thoughts, especially during the initial phase of treatment.

Can PREGANERVE-N tablet be used for conditions other than neuropathic pain?

PREGANERVE-N is specifically indicated for neuropathic pain associated with diabetic neuropathy, postherpetic neuralgia, and fibromyalgia. Its use for other conditions should be determined by a healthcare provider.

Is it safe to drive or operate machinery while taking PREGANERVE-N tablet?

Patients should exercise caution when driving or operating machinery while taking PREGANERVE-N, as it may cause dizziness or drowsiness. It is important to assess individual response to the medication and avoid activities that require mental alertness until its effects are known.

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